Mercedes Pérez‐Hernández

Disruption of blood–brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge‐like drinking model

Ana Rubio‐Araiz, Francesca Porcu, Mercedes Pérez‐Hernández et al. · Addiction Biology · 2016 · 118 citations

Bbb Permeability, Immunology, Cell Death +23

Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens

Pablo Giménez‐Gómez, Mercedes Pérez‐Hernández, María Dolores Gutiérrez‐López et al. · Neuropharmacology · 2018 · 33 citations

Neurophysiology, Addiction, Behavioral Neuroscience +13

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) produces edema due to BBB disruption induced by MMP-9 activation in rat hippocampus

Mercedes Pérez‐Hernández, María Encarnación Fernández-Valle, Ana Rubio‐Araiz et al. · Neuropharmacology · 2017 · 30 citations

Rat Hippocampus, Psychoactive Drug, Molecular Neuroscience +11

Changes in brain kynurenine levels <i>via</i> gut microbiota and gut‐barrier disruption induced by chronic ethanol exposure in mice

Pablo Giménez‐Gómez, Mercedes Pérez‐Hernández, Esther O’Shea et al. · The FASEB Journal · 2019 · 28 citations · Full text

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) disrupts blood-brain barrier integrity through a mechanism involving P2X7 receptors

Ana Rubio‐Araiz, Mercedes Pérez‐Hernández, Andrés A. Urrutia et al. · The International Journal of Neuropsychopharmacology · 2014 · 27 citations

Immunology, Psychopharmacology, Neurochemical Biomarkers +22