Sofia Ferreira

New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids

Daniela Rodrigues, Terezinha Souza, Luke Coyle et al. · Archives of Toxicology · 2021 · 55 citations · Full text

Medicine, Oncology, Pharmacology +17

Multifaceted role for p53 in pancreatic cancer suppression

Stephano S. Mello, Brittany M. Flowers, Paweł K. Mazur et al. · Proceedings of the National Academy of Sciences · 2023 · 45 citations · Full text

Medicine, Molecular Genetics, Oncology +14

Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids

Daniela Rodrigues, Luke Coyle, Barbara Füzi et al. · International Journal of Molecular Sciences · 2022 · 31 citations · Full text

Medicine, Oncology, Pharmacology +17

Quantitative Systems Toxicology Modeling To Address Key Safety Questions in Drug Development: A Focus of the TransQST Consortium

Sofia Ferreira, Ciarán Fisher, Laura I. Furlong et al. · Chemical Research in Toxicology · 2020 · 23 citations

Pharmacy, Pharmacology, Toxicology +17

Molecular insights into the <i>OGG1</i> gene, a cancer risk modifier in <i>BRCA1</i> and <i>BRCA2</i> mutations carriers

Carlos Benitéz‐Buelga, Tereza Vaclová, Sofia Ferreira et al. · Oncotarget · 2016 · 19 citations · Full text

Medicine, Genetics, Molecular Genetics +15