Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

Lara R. Malins, Justine N. deGruyter, Kevin J. Robbins, +4

Journal of the American Chemical Society

Non-ribosomal Peptide AldehydesMedicinal ChemistryBioorganic ChemistryThermodynamic ApproachBiochemistry +10

Mechanistic Studies of Peptide Self-Assembly: Transient α-Helices to Stable β-Sheets

Gai Liu, A. Prabhakar, Darryl Aucoin, +6

Journal of the American Chemical Society

Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix

Samuel Sparks, Gai Liu, Kevin J. Robbins, +1

Biochemical and Biophysical Research Communications

Protein AssemblyBiochemistryProtein FoldingNatural SciencesMolecular Biology +2

Conformational Analysis of Thioflavin T Bound to the Surface of Amyloid Fibrils

Kevin J. Robbins, Gai Liu, Veli Selmani, +1

Langmuir

Tht BoundProtein AssemblyBiochemistryProtein FoldingAmyloid Fibrils +11

Development of New Benzenesulfonamides As Potent and Selective Na_v1.7 Inhibitors for the Treatment of Pain

Yong‐Jin Wu, Jason Guernon, Jianliang Shi, +21

Journal of Medicinal Chemistry

Detection of Strongly Bound Thioflavin T Species in Amyloid Fibrils by Ligand-Detected ¹H NMR

Kevin J. Robbins, Gai Liu, Guoxing Lin, +1

The Journal of Physical Chemistry Letters

BiochemistryTht FluorescenceProtein FoldingAmyloid FibrilsSmall Molecules +10

NMR in drug design

Mary J. Harner, Luciano Mueller, Kevin J. Robbins, +1

Archives of Biochemistry and Biophysics

Magnetic Resonance SpectroscopyDrug DesignMedicineMagnetic ResonanceProtein Nmr +4

Kinetic Profile of Amyloid Formation in the Presence of an Aromatic Inhibitor by Nuclear Magnetic Resonance

Gai Liu, Jennifer Gaines, Kevin J. Robbins, +1

ACS Medicinal Chemistry Letters

Protein AssemblyAnalytical UltracentrifugationAlzheimer's DiseaseProtein FoldingProtein Misfolding +15

Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor

Jason D. Shields, David Baker, Amber Balazs, +61

Journal of Medicinal Chemistry

Discovery of morpholine-based aryl sulfonamides as Nav1.7 inhibitors

Yong‐Jin Wu, Jason Guernon, Andrea McClure, +12

Bioorganic & Medicinal Chemistry Letters