Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro

Xiaoping Ji, Jie Xiao, Xi Sheng, +2

Drug Design Development and Therapy

Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE–/– Mice by Skewing Macrophages to the M2 Phenotype

Mengqi Guo, Jie Xiao, Xi Sheng, +5

Frontiers in Pharmacology

S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization

Xuewen Wang, Shuhua Chen, Hong Xiang, +15

Biochemical Pharmacology

InflammationS1pr2/rhoa/rock1 PathwayAutophagyGastroenterologyPathology +9

Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

Jie Xiao, Tao Cai, Yuanjian Fang, +10

Journal of Neuroinflammation

Activation of GPR39 with TC-G 1008 attenuates neuroinflammation via SIRT1/PGC-1α/Nrf2 pathway post-neonatal hypoxic–ischemic injury in rats

Shucai Xie, Xili Jiang, Desislava Doycheva, +9

Journal of Neuroinflammation

Curcumin protects cardiac myocyte against hypoxia-induced apoptosis through upregulating miR-7a/b expression

Hai-Hua Geng, Rui Li, Yamin Su, +4

Biomedicine & Pharmacotherapy

InflammationHeart FailureCardiovascular DiseaseMedicineUpregulating Mir-7a/b Expression +9

Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis

Mengqi Guo, Guanlun Guo, Jie Xiao, +5

Journal of Cellular and Molecular Medicine

Vascular DiseaseCellular PhysiologyInsulin SignalingInflammationMolecular Pharmacology +20

Pituitary adenylate cyclase-activating polypeptide attenuates mitochondria-mediated oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats

Yuanjian Fang, Hui Shi, Lei Huang, +12

Free Radical Biology and Medicine

InflammationSubarachnoid HemorrhageMedicinePhysiologyApoptosis +12

Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway

Xinyu Zhang, Jie Xiao, Rui Li, +8

Vascular Pharmacology

Ampk PathwayVitamin D3NicotineVascular PharmacologyPhysiology +5

Melatonin attenuates angiotensin II-induced cardiomyocyte hypertrophy through the CyPA/CD147 signaling pathway

Hongyan Su, Jingyuan Li, Tongshuai Chen, +6

Molecular and Cellular Biochemistry

InflammationCardiac MuscleCardiomyopathyHeart FailureMolecular Physiology +9