SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study

Françoise Cottrez, Elodie Boitel, Jean-Claude Ourlin, +10

Toxicology in Vitro

Inter-laboratory StudyChemical Sensitization PotencyMedicinal ChemistryMedicineCutaneous Biology +8

Assessment of the U937 cell line for the detection of contact allergens

François Python, Carsten Goebel, Pierre Aeby

Toxicology and Applied Pharmacology

Environmental AllergyContact AllergensU937 Cell LineAllergyImmunology +6

Skin Sensitization to p-Phenylenediamine: The Diverging Roles of Oxidation and N-Acetylation for Dendritic Cell Activation and the Immune Response

Pierre Aeby, Thomas N. Sieber, H. Beck, +2

Journal of Investigative Dermatology

InflammationAllergyImmunologySkin AllergyDendritic Cell Activation +7

Use of Human In Vitro Skin Models for Accurate and Ethical Risk Assessment: Metabolic Considerations

Nicola J. Hewitt, Robert J. Edwards, Ellen Fritsche, +13

Toxicological Sciences

DermatologyOxidative StressBioanalysisNative Human SkinMetabolic Engineering +17

Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay

Françoise Cottrez, Elodie Boitel, Claude Auriault, +2

Toxicology in Vitro

Sens-is AssaySkin DevelopmentDevelopmental BiologyCutaneous BiologySkin Substitute +5

Dendritic Cells as a Tool for the Predictive Identification of Skin Sensitisation Hazard

Silvia Casati, Pierre Aeby, David A. Basketter, +15

Alternatives to Laboratory Animals

ImmunologyDermatologyImmunotherapyLaboratory Animal StudyInflammation +20

Characterization of the Sensitizing Potential of Chemicals by In Vitro Analysis of Dendritic Cell Activation and Skin Penetration

Pierre Aeby, C. Wyss, H. Beck, +3

Journal of Investigative Dermatology

InflammationVitro AnalysisImmunologySkin AllergySkin Penetration +7

Nucleotide sequence of satellite DNA contained in the eliminated genome of<i>Ascaris lumbricoides</i>

Fritz Müller, Philippe Walker, Pierre Aeby, +4

Nucleic Acids Research

Cross Talk between Keratinocytes and Dendritic Cells: Impact on the Prediction of Sensitization

Jenny Hennen, Pierre Aeby, Carsten Goebel, +4

Toxicological Sciences

Structure and genomic organization of proretrovirus-like elements partially eliminated from the somatic genome of Ascaris lumbricoides.

Pierre Aeby, Albert Spicher, Yves de Chastonay, +2

The EMBO Journal

Virus StructureAscaris LumbricoidesMolecular VirologyGeneticsPathogenesis +7