Matthew O. Brook

Allograft rejection mediated by memory T cells is resistant to regulation

Jaeseok Yang, Matthew O. Brook, Manuela Carvalho‐Gaspar et al. · Proceedings of the National Academy of Sciences · 2007 · 209 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients

Paul Harden, David Game, Birgit Sawitzki et al. · American Journal of Transplantation · 2020 · 126 citations · Full text

Pharmacy, Immunology, Nephrology +17

Location and Time-Dependent Control of Rejection by Regulatory T Cells Culminates in a Failure to Generate Memory T Cells

Manuela Carvalho‐Gaspar, Nick D. Jones, Shiqiao Luo et al. · The Journal of Immunology · 2008 · 63 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients

Matthew O. Brook, Joanna Hester, William Petchey et al. · BMJ Open · 2022 · 52 citations · Full text

Life Sciences, Immunology, Nephrology +17

Effector and Memory CD8+ T Cells Can Be Generated in Response to Alloantigen Independently of CD4+ T Cell Help

Nick D. Jones, Manuela Carvalho‐Gaspar, Shiqiao Luo et al. · The Journal of Immunology · 2006 · 42 citations

Life Sciences, Cell Biology, Immunology +17