Wishrawana S. Ratnayake

Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

Wishrawana S. Ratnayake, André H. Apostolatos, David A. Ostrov et al. · International Journal of Oncology · 2017 · 38 citations · Full text

Cell Death, Melanoma Progression, Cell Proliferation +16

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

Wishrawana S. Ratnayake, Christopher Apostolatos, André H. Apostolatos et al. · Cell Adhesion & Migration · 2018 · 25 citations · Full text

Inhibition of atypical protein kinase�C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade

Andr� Apostolatos, Wishrawana S. Ratnayake, Hla Win-Piazza et al. · International Journal of Oncology · 2018 · 24 citations · Full text

Urology, Oncology, Genitourinary Cancer +15

Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion

Wishrawana S. Ratnayake, Christopher Apostolatos, Sloan Breedy et al. · Cell Adhesion & Migration · 2021 · 20 citations · Full text

Dual inhibition of atypical PKC signaling and PI3K/Akt signaling dysregulates c-Myc to induce apoptosis in clear cell Renal Cell Carcinoma

Khandker Mohammad Khalid, Wishrawana S. Ratnayake, Christopher Apostolatos et al. · Frontiers in Oncology · 2024 · 12 citations · Full text