Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse

Manoj Garg, Yasunobu Nagata, Deepika Kanojia, +39

Blood

Prognostic impact of low allelic ratio FLT3-ITD and NPM1 mutation in acute myeloid leukemia

Masahiro Sakaguchi, Hiroki Yamaguchi, Yuho Najima, +33

Blood Advances

Prognostic impact of <i>CEBPA</i> bZIP domain mutation in acute myeloid leukemia

Satoshi Wakita, Masahiro Sakaguchi, Iekuni Oh, +50

Blood Advances

Mixed-phenotype Acute LeukemiaPathologyFavorable PrognosisTumor BiologyMyeloid Neoplasia +14

Chitin digestibility is dependent on feeding behaviors, which determine acidic chitinase mRNA levels in mammalian and poultry stomachs

Eri Tabata, Akinori Kashimura, Azusa Kikuchi, +10

Scientific Reports

Mutations of the epigenetics-modifying gene (DNMT3a, TET2, IDH1/2) at diagnosis may induce FLT3-ITD at relapse in de novo acute myeloid leukemia

Satoshi Wakita, Hiroki Yamaguchi, Ikuko Omori, +16

Leukemia

Hematological MalignancyChromatinEpigenetics-modifying GeneMixed-phenotype Acute LeukemiaGenetics +7

Gastric and intestinal proteases resistance of chicken acidic chitinase nominates chitin-containing organisms for alternative whole edible diets for poultry

Eri Tabata, Akinori Kashimura, Satoshi Wakita, +7

Scientific Reports

Acidic mammalian chitinase is a proteases-resistant glycosidase in mouse digestive system

Misa Ohno, Masahiro Kimura, Haruko Miyazaki, +11

Scientific Reports

Low-dose dasatinib in older patients with chronic myeloid leukaemia in chronic phase (DAVLEC): a single-arm, multicentre, phase 2 trial

Kazunori Murai, Hiroshi Ureshino, Takashi Kumagai, +11

The Lancet Haematology

Chronic PhaseLow-dose DasatinibHematological MalignancyOncologyHematology +6

Complex molecular genetic abnormalities involving three or more genetic mutations are important prognostic factors for acute myeloid leukemia

Satoshi Wakita, Hiroki Yamaguchi, Tomoyuki Ueki, +19

Leukemia

Hematological MalignancyChromatinMore Genetic MutationsMedicineGenetics +9

Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia

Satoshi Wakita, Hiroki Yamaguchi, Keisuke Miyake, +4

Leukemia

Hematological MalignancyPrognostic AnalysesMedicineMixed-phenotype Acute LeukemiaHematology +9