Timothy P. Twaroski

Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress☆1☆Contents reflect the views of the authors and do not represent any official view(s) of NIEHS, EPA, or DOD.1Abbreviations: PCBs, polychlorinated biphenyls; GST, glutathione transferase; GPX, glutathione peroxidase; SeGPX, selenium-dependent glutathione peroxidase; GR, glutathione reductase; MOPS, 3-{N-morpholino}propane sulfonic acid buffer; CDNB, 1-chloro-2,4-dinitrobenzene; PB, phenobarbital; 3-MC, 3-methylcholanthrene; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; AhR, aryl hydrocarbon receptor; XRE, xenobiotic response element; ROS, reactive oxygen species; and GSPx1, cytosolic selenium-dependent glutathione peroxidase gene.

Timothy P. Twaroski, Michelle L. O’Brien, Larry W. Robertson · Biochemical Pharmacology · 2001 · 100 citations

Pharmacy, Environmental Sciences, Toxicology +17

Polychlorinated Biphenyl-Induced Effects on Metabolic Enzymes, AP-1 Binding, Vitamin E, and Oxidative Stress in the Rat Liver

Timothy P. Twaroski, Michelle L. O’Brien, Nicolas Larmonier et al. · Toxicology and Applied Pharmacology · 2001 · 81 citations

Pharmacy, Biochemistry, Toxicology +17

Redox Cycling of 2-(x′-Mono, -di, -trichlorophenyl)- 1,4-benzoquinones, Oxidation Products of Polychlorinated Biphenyls

Mitch R. McLean, Timothy P. Twaroski, Larry W. Robertson · Archives of Biochemistry and Biophysics · 2000 · 69 citations

Natural Sciences, Chemistry, Toxicology +15

2,4,4′‐trichlorobiphenyl increases STAT5 transcriptional activity

Greg G. Oakley, Amy L. Roe, Robert A. Blouin et al. · Molecular Carcinogenesis · 2001 · 12 citations

Pharmacy, Oncology, Toxicology +14