Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression

Marc Pearton, Verena Saller, Sion Coulman, +4

Journal of Controlled Release

Tissue EngineeringNanomedicineDna NanotechnologyEngineeringBiofabrication +9

In Vivo, In Situ Imaging of Microneedle Insertion into the Skin of Human Volunteers Using Optical Coherence Tomography

Sion Coulman, James C. Birchall, Aneesh Alex, +5

Pharmaceutical Research

Situ ImagingTissue ImagingEngineeringMicroscopyBiomedical Imaging +6

Gene Delivery to the Epidermal Cells of Human Skin Explants Using Microfabricated Microneedles and Hydrogel Formulations

Marc Pearton, Christopher J. Allender, Keith L. Brain, +5

Pharmaceutical Research

Regenerative MedicineTissue EngineeringEngineeringMicro-encapsulationBiofabrication +7

Cutaneous DNA delivery and gene expression in <i>ex vivo</i> human skin explants via wet-etch microfabricated microneedles

James C. Birchall, Sion Coulman, Marc Pearton, +6

Journal of drug targeting

Microneedle Delivery of H5N1 Influenza Virus-Like Particles to the Skin Induces Long-Lasting B- and T-Cell Responses in Mice

Jae-Min Song, Yeu‐Chun Kim, Aleksandr S. Lipatov, +11

Clinical and Vaccine Immunology

Humoral ResponseImmunologyHuman Skin ModelFlu VaccinationInfluenza Vaccines +15

Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin

Marc Pearton, Sang‐Moo Kang, Jae-Min Song, +7

Vaccine

VaccinationMucosal VaccinationCross-protectionImmunologyVirology +6

Development of an ex vivo human skin model for intradermal vaccination: Tissue viability and Langerhans cell behaviour

Keng Wooi Ng, Marc Pearton, Sion Coulman, +5

Vaccine

VaccinationVaccinologyMucosal VaccinationTissue ViabilityVaccine Development +8

Changes in Human Langerhans Cells Following Intradermal Injection of Influenza Virus-Like Particle Vaccines

Marc Pearton, Sang‐Moo Kang, Jae Min Song, +4

PLoS ONE

VaccinationLc MigrationHuman Breast SkinExcised Human SkinMucosal Vaccination +12

Host Responses in Human Skin After Conventional Intradermal Injection or Microneedle Administration of Virus‐Like‐Particle Influenza Vaccine

Marc Pearton, Daniela Pirri, Sang‐Moo Kang, +2

Advanced Healthcare Materials