A strategy for structuring and reporting a read-across prediction of toxicity

T.W. Schultz, Patric Amcoff, Elisabet Berggren, +7

Regulatory Toxicology and Pharmacology

Toxicology TestingRead-across PredictionEnvironmental HealthToxicologyBiostatistics +20

Ab initio chemical safety assessment: A workflow based on exposure considerations and non-animal methods

Elisabet Berggren, Andrew White, Gladys Ouédraogo, +8

Computational Toxicology

Chemical SafetyExposure ConsiderationsMedicineChemical HazardForensic Toxicology +8

Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop

Carl Westmoreland, Hans Bender, John E. Doe, +13

Regulatory Toxicology and Pharmacology

EngineeringSafety ScienceToxicology TestingInherent SafetyRegulatory Safety Science +19

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Matthew Dent, Eric Vaillancourt, Russell S. Thomas, +25

Regulatory Toxicology and Pharmacology

Safety ScienceInherent SafetyInjury PreventionRisk AnalysisRegulatory Safety Science +17

Relative potency of fifteen pyrrolizidine alkaloids to induce DNA damage as measured by micronucleus induction in HepaRG human liver cells

Ashley Allemang, Catherine Mahony, Cathy Lester, +1

Food and Chemical Toxicology

Fifteen Pyrrolizidine AlkaloidsDna DamageBiochemistryMedicineLiver Physiology +9

Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments

Karen Blackburn, Donald L. Bjerke, George P. Daston, +5

Regulatory Toxicology and Pharmacology

Predictive ToxicologyBiochemistryMedicineMass SpectrometryToxicology Testing +12

SEURAT: Safety Evaluation Ultimately Replacing Animal Testing—Recommendations for future research in the field of predictive toxicology

George P. Daston, Derek J. Knight, Michael Schwarz, +4

Archives of Toxicology

Predictive ToxicologyForensic ToxicologyVeterinary ScienceToxicology TestingToxicology +4

New framework for a non-animal approach adequately assures the safety of cosmetic ingredients – A case study on caffeine

Dagmar Bury, Camilla Alexander‐White, Harvey J. Clewell, +14

Regulatory Toxicology and Pharmacology

Dietary ExposureDermatologyPhysiologically-based Pharmacokinetic ModelingFood ToxicologyNon-animal Approach +17

Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment – A case study with parabens

Gladys Ouédraogo, Camilla Alexander‐White, Dagmar Bury, +24

Regulatory Toxicology and Pharmacology

EngineeringSafety SciencePara-hydroxybenzoic AcidRegulatory Safety ScienceDermatology +18

Quantitative risk assessment for the induction of allergic contact dermatitis: uncertainty factors for mucosal exposures

Miranda A. Farage, Donald L. Bjerke, Catherine Mahony, +2

Contact Dermatitis

AsthmaAllergy MedicineSkin AllergyDermatologyThreshold Noael +18