Karen L. Onions

Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease

Raina Ramnath, Matthew Butler, Georgina Newman et al. · Kidney International · 2019 · 106 citations · Full text

Aldosterone induces albuminuria via matrix metalloproteinase–dependent damage of the endothelial glycocalyx

Matthew Butler, Raina Ramnath, Hiroyuki Kadoya et al. · Kidney International · 2018 · 89 citations · Full text

Urology, Endothelial Glycocalyx, Physiology +8

A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli

Sara Desideri, Karen L. Onions, Yan Qiu et al. · Kidney International · 2018 · 70 citations · Full text

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy

Karen L. Onions, Monica Gamez, Nicola Buckner et al. · Diabetes · 2018 · 70 citations · Full text

Immunology, Protects Against Alterations, Vegf Receptor Alterations +18

Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx

Michael Crompton, Joanne Ferguson, Raina Ramnath et al. · JCI Insight · 2023 · 57 citations · Full text

Glomerular Disease, Renal Pathology, Renal Inflammation +22