Alexander D. Blanchette

Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes

Sarah D. Burnett, Alexander D. Blanchette, Fabian A. Grimm et al. · Toxicology and Applied Pharmacology · 2019 · 98 citations · Full text

Life Sciences, Cell Biology, Toxicology +7

Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors

Sarah D. Burnett, Alexander D. Blanchette, Weihsueh A. Chiu et al. · Chemical Research in Toxicology · 2021 · 63 citations · Full text

Pharmacy, Cardiology, Toxicology +13

Thorough QT/QTc in a Dish: An <i>In Vitro</i> Human Model That Accurately Predicts Clinical Concentration‐QTc Relationships

Alexander D. Blanchette, Fabian A. Grimm, Chimeddulam Dalaijamts et al. · Clinical Pharmacology & Therapeutics · 2018 · 61 citations · Full text

Medicine, Cardiology, Pharmacology +14

A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an <i>In Vitro</i> Human Model

Alexander D. Blanchette, Sarah D. Burnett, Fabian A. Grimm et al. · Toxicological Sciences · 2020 · 59 citations · Full text

Pharmacy, Pharmacology, Toxicology +13

A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability

Alexander D. Blanchette, Sarah D. Burnett, Ivan Rusyn et al. · Journal of Pharmacological and Toxicological Methods · 2022 · 43 citations · Full text

Pharmacy, Pharmacology, Toxicology +7