Alexander D. Blanchette

Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes

Sarah D. Burnett, Alexander D. Blanchette, Fabian A. Grimm et al. · Toxicology and Applied Pharmacology · 2019 · 94 citations · Full text

Induced Pluripotent Stem Cell, Heart Failure, Medicine +13

Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors

Sarah D. Burnett, Alexander D. Blanchette, Weihsueh A. Chiu et al. · Chemical Research in Toxicology · 2021 · 62 citations · Full text

Thorough QT/QTc in a Dish: An <i>In Vitro</i> Human Model That Accurately Predicts Clinical Concentration‐QTc Relationships

Alexander D. Blanchette, Fabian A. Grimm, Chimeddulam Dalaijamts et al. · Clinical Pharmacology & Therapeutics · 2018 · 60 citations · Full text

Heart Failure, Thorough Qt/qtc, Cardiovascular Toxicity +17

A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an <i>In Vitro</i> Human Model

Alexander D. Blanchette, Sarah D. Burnett, Fabian A. Grimm et al. · Toxicological Sciences · 2020 · 57 citations · Full text

A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability

Alexander D. Blanchette, Sarah D. Burnett, Ivan Rusyn et al. · Journal of Pharmacological and Toxicological Methods · 2022 · 42 citations · Full text

Cardiovascular Disease, Medicine, Clinical Population +5