Ignacio J. General

Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis

Jessica LaRusch, Jinsei Jung, Ignacio J. General et al. · PLoS Genetics · 2014 · 177 citations · Full text

Inflammation, Cftr Functional Variants, Fibrosis +14

ATPase Subdomain IA Is a Mediator of Interdomain Allostery in Hsp70 Molecular Chaperones

Ignacio J. General, Ying Liu, Mandy E. Blackburn et al. · PLoS Computational Biology · 2014 · 156 citations · Full text

Protein Assembly, Molecular Biology, Hsp70 Domains +19

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer

Vivian Wai Yan Lui, Noah D. Peyser, Patrick Kwok‐Shing Ng et al. · Proceedings of the National Academy of Sciences · 2014 · 102 citations · Full text

A Note on the Standard State’s Binding Free Energy

Ignacio J. General · Journal of Chemical Theory and Computation · 2010 · 64 citations

Quantum Dynamic, Engineering, Computational Chemistry +17

Convergence and equilibrium in molecular dynamics simulations

Franco Ormeño, Ignacio J. General · Communications Chemistry · 2024 · 50 citations · Full text