Pascal Peschard

Mutation of the c-Cbl TKB Domain Binding Site on the Met Receptor Tyrosine Kinase Converts It into a Transforming Protein

Pascal Peschard, Tanya M. Fournier, Louie Lamorte et al. · Molecular Cell · 2001 · 450 citations · Full text

Transforming Protein, Signal Transduction, Signaling Pathway +6

Escape from Cbl-mediated downregulation

Pascal Peschard, Morag Park · Cancer Cell · 2003 · 234 citations · Full text

Cannabis Use, Medicine, Cbl-mediated Downregulation +3

Met/Hepatocyte Growth Factor Receptor Ubiquitination Suppresses Transformation and Is Required for Hrs Phosphorylation

Jasmine V. Abella, Pascal Peschard, Monica A. Naujokas et al. · Molecular and Cellular Biology · 2005 · 206 citations · Full text

Met Internalization, Hrs Phosphorylation, Met Receptor +18

Structural Basis for Ubiquitin-Mediated Dimerization and Activation of the Ubiquitin Protein Ligase Cbl-b

Pascal Peschard, Guennadi Kozlov, Lin Tong et al. · Molecular Cell · 2007 · 121 citations · Full text

Protein Function, Ubiquitin-mediated Dimerization, Molecular Biology +4

A Conserved DpYR Motif in the Juxtamembrane Domain of the Met Receptor Family Forms an Atypical c-Cbl/Cbl-b Tyrosine Kinase Binding Domain Binding Site Required for Suppression of Oncogenic Activation

Pascal Peschard, Noboru Ishiyama, Lin Tong et al. · Journal of Biological Chemistry · 2004 · 117 citations · Full text