Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume

Greetje Vande Velde, Jennifer Poelmans, Ellen De Langhe, +4

Disease Models & Mechanisms

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5

Andrew S. Gilbert, Paula I. Seoane, Poppy Sephton-Clark, +12

Science Advances

Radiosafe micro-computed tomography for longitudinal evaluation of murine disease models

Nathalie Berghen, Kaat Dekoster, Eyra Marien, +13

Scientific Reports

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

Liesbeth Vanherp, Alexandra Ristani, Jennifer Poelmans, +6

Disease Models & Mechanisms

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

Muhammad Ali, Eirini Giannakopoulou, Yingqian Li, +30

Nature Biotechnology

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Eirini Giannakopoulou, Madeleine Lehander, Stina Virding Culleton, +26

Nature Cancer

Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells

Joana Carrelha, Stefania Mazzi, Axel Winroth, +26

Nature Immunology

Longitudinal, in vivo assessment of invasive pulmonary aspergillosis in mice by computed tomography and magnetic resonance imaging

Jennifer Poelmans, Amy Hillen, Liesbeth Vanherp, +6

Laboratory Investigation

Multiple Pulmonary NodulePathologyInvasive Pulmonary AspergillosisVivo AssessmentPulmonary Fibrosis +4

A Multimodal Imaging Approach Enables <i>In Vivo</i> Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis

Jennifer Poelmans, Uwe Himmelreich, Liesbeth Vanherp, +8

Antimicrobial Agents and Chemotherapy

Trehalose as quantitative biomarker for in vivo diagnosis and treatment follow-up in cryptococcomas

Liesbeth Vanherp, Jennifer Poelmans, Akila Weerasekera, +6

Translational research

Diagnostic MycologyMolecular Diagnostic TechniquesTreatment Follow-upPathologyClinical Mycology +5