T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

Muhammad Ali, Eirini Giannakopoulou, Yingqian Li, +30

Nature Biotechnology

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Eirini Giannakopoulou, Madeleine Lehander, Stina Virding Culleton, +26

Nature Cancer

Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells

Joana Carrelha, Stefania Mazzi, Axel Winroth, +26

Nature Immunology

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model

Brahim Arkoun, Elie Robert, Fabien Boudia, +24

Journal of Clinical Investigation

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Anita Roy, Larissa Lordier, Stefania Mazzi, +6

Blood

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Tiago C. Luís, Nikolaos Barkas, Joana Carrelha, +18

Nature Communications

Dual role of EZH2 in megakaryocyte differentiation

Stefania Mazzi, Philippe Dessen, Mathieu Vieira, +16

Blood

Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation

Marios Dimitriou, Teresa Mortera‐Blanco, Magnus Tobiasson, +13

Blood