Detection of <i>K‐ras</i> gene mutation by liquid biopsy in patients with pancreatic cancer

Hideaki Kinugasa, Kazuhiro Nouso, Koji Miyahara, +7

Cancer

Fibroblast growth factor-2–mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma

Osamu Maehara, Goki Suda, Mitsuteru Natsuizaka, +20

Carcinogenesis

Droplet digital PCR measurement of HER2 in patients with gastric cancer

Hideaki Kinugasa, Kazuhiro Nouso, Takehiro Tanaka, +6

British Journal of Cancer

Leucine-rich alpha-2 glycoprotein as a marker of mucosal healing in inflammatory bowel disease

Eriko Yasutomi, Toshihiro Inokuchi, Sakiko Hiraoka, +17

Scientific Reports

InflammationMucosal HealingAnti-inflammatoryAutoimmune DiseaseMucosal Immunology +9

Mitochondrial SOD2 regulates epithelial–mesenchymal transition and cell populations defined by differential CD44 expression

Hideaki Kinugasa, Kelly A. Whelan, Koji Tanaka, +12

Oncogene

Differential Cd44 ExpressionMitochondrial FunctionMitochondrial DynamicCell SignalingMitochondrial Sod2 +7

Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation

Masahiro Takahara, Akinobu Takaki, Sakiko Hiraoka, +16

Scientific Reports

IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.

Mitsuteru Natsuizaka, Hideaki Kinugasa, Shingo Kagawa, +13

PubMed

Esophageal CancerPathologyEsophageal Cancer GrowthCancer BiologyRedox Biology +16

Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities

Shunsuke Kagawa, Mitsuteru Natsuizaka, Kelly A. Whelan, +13

Oncogene

Tumor-suppressor ActivitiesCell RegulationMedicineDifferential Notch1-dependent OncogenicCellular Senescence +5

Liquid biopsy of bile for the molecular diagnosis of gallbladder cancer

Hideaki Kinugasa, Kazuhiro Nouso, Soichiro Ako, +5

Cancer Biology & Therapy

EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition

Fumiyuki Sato, Yoshimasa Kubota, Mitsuteru Natsuizaka, +14

Cancer Biology & Therapy

Esophageal CancerPathologyEgfr InhibitorsCancer BiologyCancer Stem-like Cells +17