Edward Owen

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

Annie N. Cowell, Eva S. Istvan, Amanda K. Lukens et al. · Science · 2018 · 273 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

Yevgeniya Antonova‐Koch, Stephan Meister, Matthew Abraham et al. · Science · 2018 · 140 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery

James M. Murithi, Edward Owen, Eva S. Istvan et al. · Cell chemical biology · 2019 · 96 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Manu Vanaerschot, James M. Murithi, Charisse Flerida A. Pasaje et al. · Cell chemical biology · 2020 · 91 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Robert L. Summers, Charisse Flerida A. Pasaje, João Pedro Pisco et al. · Cell chemical biology · 2021 · 81 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16