Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group

William Kemnitzer, John Drewe, Songchun Jiang, +18

Journal of Medicinal Chemistry

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions

William Kemnitzer, Shailaja Kasibhatla, Songchun Jiang, +17

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +9

Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of <i>N</i>-Alkyl Substituted Pyrrole Fused at the 7,8-Positions

William Kemnitzer, John Drewe, Songchun Jiang, +11

Journal of Medicinal Chemistry

Chemoprevention StrategyApoptosisCell DeathNew SeriesHeterocycle Chemistry +15

Discovery and mechanism of action of a novel series of apoptosis inducers with potential vascular targeting activity

Shailaja Kasibhatla, Henriette Gourdeau, Karen Meerovitch, +11

Molecular Cancer Therapeutics

Discovery of 4-Aryl-4<i>H</i>-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions

William Kemnitzer, John Drewe, Songchun Jiang, +10

Journal of Medicinal Chemistry

ApoptosisCell DeathMolecular BiologyNew SeriesFused Rings +15

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions

William Kemnitzer, Songchun Jiang, Yan Wang, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +11

Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay

William Kemnitzer, Songchun Jiang, Hong Zhang, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +9

Enantioselective total synthesis of salicylihalamides A and B

Denis Labrecque, Sylvie Charron, Rabindra Rej, +2

Tetrahedron Letters

Salicylihalamides AOrganic ChemistryChemistryPharmacologySynthetic Chemistry +2

Hybrid Antibacterials. DNA Polymerase−Topoisomerase Inhibitors

Chengxin Zhi, Zheng‐Yu Long, Andrzej Manikowski, +18

Journal of Medicinal Chemistry

Synthesis and Antibacterial Activity of 3-Substituted-6-(3-ethyl-4-methylanilino)uracils

Chengxin Zhi, Zheng‐Yu Long, Andrzej Manikowski, +12

Journal of Medicinal Chemistry