Ronald K. Scheule

Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung

Edward R. Lee, John Marshall, Craig Siegel et al. · Human Gene Therapy · 1996 · 444 citations

Pharmacy, Molecular Biology, Pharmaceutics +17

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby et al. · The Lancet Respiratory Medicine · 2015 · 424 citations · Full text

Pharmacy, Molecular Medicine, Pharmacotherapy +17

Basis of Pulmonary Toxicity Associated with Cationic Lipid-Mediated Gene Transfer to the Mammalian Lung

Ronald K. Scheule, Judith A. St. George, Rebecca G. Bagley et al. · Human Gene Therapy · 1997 · 251 citations

Pharmacy, Pharmacology, Toxicology +17

Comprehensive Analysis of the Acute Toxicities Induced by Systemic Administration of Cationic Lipid:Plasmid DNA Complexes in Mice

Jennifer D. Tousignant, Amy Gates, Laurie Ingram et al. · Human Gene Therapy · 2000 · 234 citations

Veterinary Medicine, Pharmacology, Toxicology +17

CpG-Depleted Plasmid DNA Vectors with Enhanced Safety and Long-Term Gene Expression in Vivo

Nelson S. Yew, Hongmei Zhao, Malgorzata Przybylska et al. · Molecular Therapy · 2002 · 221 citations · Full text

Pharmacy, Molecular Biology, Molecular Pharmaceutics +17