Christie Verscharen

Versican V1 Proteolysis in Human Aorta in Vivo Occurs at the Glu441-Ala442 Bond, a Site That Is Cleaved by Recombinant ADAMTS-1 and ADAMTS-4

John D. Sandy, Jennifer Westling, Richard D. Kenagy et al. · Journal of Biological Chemistry · 2001 · 452 citations · Full text

Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo

John D. Sandy, Christie Verscharen · Biochemical Journal · 2001 · 187 citations · Full text

Chondrocyte-mediated catabolism of aggrecan: aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine

John D. Sandy, Dan Gamett, Vivian P. Thompson et al. · Biochemical Journal · 1998 · 156 citations · Full text

Laboratory Immunology, Mm Glutamine, Immunology +21

Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo

John D. Sandy, Christie Verscharen · Biochemical Journal · 2001 · 115 citations

Human Knee Cartilage, Excessive Adamts Activity, Orthopaedic Surgery +19

The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1

John D. Sandy, Vivian P. Thompson, Kurt Doege et al. · Biochemical Journal · 2000 · 53 citations · Full text