Chang Sin Park

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models

C.Y. Daniel Lee, Anthony Daggett, Xiaofeng Gu et al. · Neuron · 2018 · 410 citations · Full text

Disease Models, Neurodegenerative Diseases, Molecular Neuroscience +15

Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward

Yijun Cui, Sean B. Ostlund, Alex S. James et al. · Nature Neuroscience · 2014 · 154 citations · Full text

Striatal Direct-pathway Neurons, Synaptic Plasticity, Addiction +11

An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice

B. Wilburn, Dobrila D. Rudnicki, Jing Zhao et al. · Neuron · 2011 · 131 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Molecular Neuroscience +8

N17 Modifies Mutant Huntingtin Nuclear Pathogenesis and Severity of Disease in HD BAC Transgenic Mice

Xiaofeng Gu, Jeffrey P. Cantle, Erin R. Greiner et al. · Neuron · 2015 · 84 citations · Full text

Knockout Mouse, Immune Cell Development, Genetics +5

Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice

Matthew B. Veldman, Chang Sin Park, Charles M. Eyermann et al. · Neuron · 2020 · 67 citations · Full text

Neurodegenerative Diseases, Cre-dependent Morf Mice, Neuroanatomy +10