α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

Michela Zaltieri, Jéssica Grigoletto, Francesca Longhena, +12

Journal of Cell Science

Synaptic TransmissionNeurotransmitterMolecular BiologyNeurotransmissionDopamine Neurons +19

Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson’s disease

Adrianne F. Pike, Francesca Longhena, Gaia Faustini, +11

Journal of Neuroinflammation

Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

Gaia Faustini, Francesca Longhena, Tatiana Varanita, +7

Acta Neuropathologica

Synaptic PlasticityNeurodegenerative DiseasesNeurobiology Of DiseaseStriatal Synaptic DamageDegenerative Diseases +13

Synapsin III is a key component of α‐synuclein fibrils in Lewy bodies of PD brains

Francesca Longhena, Gaia Faustini, Tatiana Varanita, +11

Brain Pathology

Synaptic TransmissionMolecular BiologyNeurochemical BiomarkersCellular NeurobiologySynaptic Signaling +23

Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes

Alice Filippini, Veronica Mutti, Gaia Faustini, +17

Glia

Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma

Fiorella Faggi, Nicola Chiarelli, Marina Colombi, +12

Laboratory Investigation

Cell DivisionMedicineCell ProliferationCell BiologyCell Growth +8

Anionic liposomes for small interfering ribonucleic acid (siRNA) delivery to primary neuronal cells: Evaluation of alpha-synuclein knockdown efficacy

Michele Schlich, Francesca Longhena, Gaia Faustini, +5

Nano Research

Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells

Gaia Faustini, Elena Marchesan, Laura Zonta, +6

Oxidative Medicine and Cellular Longevity

Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate

Gaia Faustini, Francesca Longhena, Agostino Bruno, +13

Neurobiology of Disease

Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure

Laura Navarria, Michela Zaltieri, Francesca Longhena, +4

Neurochemistry International

MedicineNeuropharmacologyNeurochemical BiomarkersNeuroprotectionNeurology +7