James E. Rowedder

Production of mouse epidermal growth factor in yeast: high-level secretion using Pichia pastoris strains containing multiple gene copies

Jeffrey J. Clare, Michael A. Romanes, F. B. Rayment et al. · Gene · 1991 · 331 citations

Life Sciences, Microbiology, Molecular Biology +10

Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin

David A. Lomas, James A. Irving, Christopher C. Arico-Muendel et al. · EMBO Molecular Medicine · 2021 · 64 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Discovery of (<i>S</i>)-3-(3-(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)phenyl)-4-((<i>R</i>)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic α_vβ₆ Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis

Panayiotis A. Procopiou, Niall A. Anderson, John W. Barrett et al. · Journal of Medicinal Chemistry · 2018 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Direct Measurement of the Binding of RAS to Neurofibromin Using a Scintillation Proximity Assay

Richard Skinner, Mauro Picardo, N.M. Gane et al. · Analytical Biochemistry · 1994 · 27 citations

Life Sciences, Biophysics, Neuroscience +5

Structure Activity Relationships of α_v Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents

James Truslow Adams, Edward C. Anderson, Emma E. Blackham et al. · ACS Medicinal Chemistry Letters · 2014 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15