The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

Charles Gauthier, Véronique Leblais, Lester Kobzik, +5

Journal of Clinical Investigation

Heart FailureNitric OxidePharmacotherapySocial SciencesCardiac Contraction +14

Beta 3‐adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium‐derived nitric oxide in rat thoracic aorta

Jean‐Noël Trochu, Véronique Leblais, Yohann Rautureau, +4

British Journal of Pharmacology

Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia

Fleur Fresquet, Fabrice Pourageaud, Véronique Leblais, +4

British Journal of Pharmacology

Phosphatidylinositol 3-Kinase Functionally Compartmentalizes the Concurrent G _s Signaling During β ₂ -Adrenergic Stimulation

Su‐Hyun Jo, Véronique Leblais, Ping H. Wang, +2

Circulation Research

Interspecies differences in the cardiac negative inotropic effects of beta(3)-adrenoceptor agonists.

Charles Gauthier, Geneviève Tavernier, Jean‐Noël Trochu, +5

PubMed

Cardiovascular PharmacologyDecreased ContractilityPharmacotherapyMolecular PharmacologyNeuroendocrine Mechanism +15

Impairment of NO-Dependent Relaxation in Intralobar Pulmonary Arteries: Comparison of Urban Particulate Matter and Manufactured Nanoparticles

Arnaud Courtois, Pascal Andujar, Yannick Ladeiro, +9

Environmental Health Perspectives

Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive

Zineb Hakkou, Alexandre Maciuk, Véronique Leblais, +11

Biomedicine & Pharmacotherapy

HypertensionMedicineAntihypertensive TherapyPhysiologyVascular Pharmacology +6

Phosphatidylinositol 3-Kinase Offsets cAMP-Mediated Positive Inotropic Effect via Inhibiting Ca ²⁺ Influx in Cardiomyocytes

Véronique Leblais, Su‐Hyun Jo, Khalid Chakir, +6

Circulation Research

Cardiac MusclePhosphoinositide 3-KinaseSignal TransductionMolecular PhysiologyPi3k Activity +11

 -adrenergic relaxation in pulmonary arteries: preservation of the endothelial nitric oxide-dependent  2 component in pulmonary hypertension

Véronique Leblais, E Delannoy, Fleur Fresquet, +8

Cardiovascular Research

Role of Gi/o-Src kinase-PI3K/Akt pathway and caveolin-1 in β2-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery

Sébastien Banquet, E Delannoy, Abdelali Agouni, +6

Cellular Signalling

Molecular PhysiologySignal TransductionPulmonary CirculationGi/o-src Kinase-pi3k/akt PathwayMedicine +10