T. Shirotani

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells

Koji Sakai, Takeshi Nishikawa, Mihoshi Suefuji et al. · Biochemical and Biophysical Research Communications · 2003 · 325 citations

Pancreatic β-Cells, Mitochondrial Function, Biochemistry +10

Identification of two enhancer elements in the gene encoding the type 1 glucose transporter from the mouse which are responsive to serum, growth factor, and oncogenes.

T. Murakami, Takeshi Nishiyama, T. Shirotani et al. · Journal of Biological Chemistry · 1992 · 135 citations · Full text

Molecular Regulation, Glycobiology, Metabolic Remodeling +22

A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians

Kyong Soo Park, Juliana C.N. Chan, Lee‐Ming Chuang et al. · Diabetologia · 2008 · 109 citations · Full text

Metabolic Syndrome, Genetic Determinant, Mitochondrial Function +10

A cluster of four Sp1 binding sites required for efficient expression of the human insulin receptor gene

Eiichi Araki, T Murakami, T. Shirotani et al. · Journal of Biological Chemistry · 1991 · 88 citations · Full text

Molecular Biology, Insulin Signaling, Transcriptional Regulation +16

A carboxy-terminal truncation of human alpha-galactosidase A in a heterozygous female with Fabry disease and modification of the enzymatic activity by the carboxy-terminal domain. Increased, reduced, or absent enzyme activity depending on number of amino acid residues deleted.

Nobuhiro Miyamura, Eiichi Araki, Kouki Matsuda et al. · Journal of Clinical Investigation · 1996 · 39 citations · Full text

Genetics, Glycobiology, Pathology +18