Sofya V. Lushchekina

Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease

Sofya V. Lushchekina, Natalia P. Boltneva, V. V. Grigoriev et al. · Scientific Reports · 2015 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease

Irina V. Zueva, José Dias, Sofya V. Lushchekina et al. · Neuropharmacology · 2019 · 90 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents

Sofya V. Lushchekina, Lawrence M. Schopfer, Bella L. Grigorenko et al. · Frontiers in Pharmacology · 2018 · 73 citations · Full text

Life Sciences, Pharmacology, Toxicology +13

Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer’s disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation

N. V. Kovaleva, Natalia P. Boltneva, Sofya V. Lushchekina et al. · Bioorganic Chemistry · 2019 · 72 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Characterization of a complete cycle of acetylcholinesterase catalysis by ab initio QM/MM modeling

Alexander V. Nemukhin, Sofya V. Lushchekina, Anastasia V. Bochenkova et al. · Journal of Molecular Modeling · 2008 · 69 citations

Life Sciences, Biochemistry, Chemistry +16