Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin, +8

Cell

Rna-guided Crispr Cas9GeneticsMolecular BiologyGenetic EngineeringGene Editing +5

Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos

Azusa Inoue, Yi Zhang

Science

Maternal H3K27me3 controls DNA methylation-independent imprinting

Azusa Inoue, Lan Jiang, Falong Lu, +2

Nature

ChromatinEpigenetic ChangeGeneticsDna MethylationEpigenomics +4

Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation

Shogo Matoba, Yuting Liu, Falong Lu, +4

Cell

ChromatinDevelopmental BiologyChromatin RemodelingSomatic Cell GeneticsEpigenetic Change +12

Establishing Chromatin Regulatory Landscape during Mouse Preimplantation Development

Falong Lu, Yuting Liu, Azusa Inoue, +3

Cell

Tet1 controls meiosis by regulating meiotic gene expression

Shinpei Yamaguchi, Kwonho Hong, Rui Liu, +5

Nature

ChromatinTranscriptional RegulationCell DivisionMeiotic Gene ExpressionGenetics +5

Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development

Azusa Inoue, Li Shen, Qing Dai, +2

Cell Research

Knockout MouseMouse Preimplantation DevelopmentDevelopmental BiologyCell DivisionGenetics +7

Tet3 and DNA Replication Mediate Demethylation of Both the Maternal and Paternal Genomes in Mouse Zygotes

Li Shen, Azusa Inoue, Jin He, +3

Cell stem cell

ChromatinMedicineGeneticsNatural SciencesGenome Structure +11

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming

Shinpei Yamaguchi, Kwonho Hong, Rui Liu, +4

Cell Research

Epigenetic ChangeGeneticsDna MethylationPericentric 5HmcMolecular Biology +19

Nucleosome assembly is required for nuclear pore complex assembly in mouse zygotes

Azusa Inoue, Yi Zhang

Nature Structural & Molecular Biology

ChromatinNuclear StructureChromatin StructureChromatin RemodelingMedicine +9