David G. Alberg

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

J. Liu, Mark W. Albers, Thomas J. Wandless et al. · Biochemistry · 1992 · 560 citations

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.

Ramsay Fuleihan, N Ramesh, A Horner et al. · Journal of Clinical Investigation · 1994 · 140 citations · Full text

Allergy, Autoimmune Disease, T-regulatory Cell +13

Cyclosporine- and FK506-induced sympathetic activation correlates with calcineurin-mediated inhibition of T-cell signaling.

T Lyson, Leann D. Ermel, Peter J. Belshaw et al. · Circulation Research · 1993 · 89 citations

Immunology, T-cell Signaling, Experimental Pharmacology +17

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A

Hengming Ke, Dale Mayrose, Peter J. Belshaw et al. · Structure · 1994 · 77 citations · Full text

Crystal Structure, Heterocyclic, Biochemistry +9

Structure-Based Design of a Cyclophilin-Calcineurin Bridging Ligand

David G. Alberg, Stuart L. Schreiber · Science · 1993 · 76 citations

Combinatorial Chemistry, Signal Transduction, Protein Assembly +14