Thomas J. Sproule

Enhanced antibody half-life improves in vivo activity

Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton et al. · Nature Biotechnology · 2010 · 625 citations · Full text

Antibody Half-life Improves, Immunology, Antibody Screening +5

The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs

Derry C. Roopenian, Gregory J. Christianson, Thomas J. Sproule et al. · The Journal of Immunology · 2003 · 446 citations

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease

Stefka B. Petkova, Shreeram Akilesh, Thomas J. Sproule et al. · International Immunology · 2006 · 305 citations

Immunohematology, Enhanced Half-life, Laboratory Immunology +24

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-<i>Yaa</i>mice

Jason A. Bubier, Thomas J. Sproule, Oded Foreman et al. · Proceedings of the National Academy of Sciences · 2009 · 295 citations · Full text

The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease

Shreeram Akilesh, Stefka B. Petkova, Thomas J. Sproule et al. · Journal of Clinical Investigation · 2004 · 188 citations · Full text