J.H.M. Schellens

Relationship between the metabolism of antipyrine, hexobarbitone and theophylline in man as assessed by a ‘cocktail’ approach.

J.H.M. Schellens, JH van der Wart, Meindert Danhof et al. · British Journal of Clinical Pharmacology · 1988 · 54 citations · Full text

Drug Oxidation Activity, Pharmacotherapy, Experimental Pharmacology +17

The Accumulation of Topotecan in 9L Glioma and in Brain Parenchyma with and without Dexamethasone Administration

C.S.M. Straathof, Martin J. van den Bent, Walter J. Loos et al. · Journal of Neuro-Oncology · 1999 · 26 citations

Neuro-oncology, Tumoral Pathology, Tumor Innervation +13

Relationship between mephenytoin oxidation polymorphism and phenytoin, methylphenytoin and phenobarbitone hydroxylation assessed in a phenotyped panel of healthy subjects.

J.H.M. Schellens, JH van der Wart, DD Breimer · British Journal of Clinical Pharmacology · 1990 · 14 citations · Full text

604 Safety and Recommended Phase II Dose (RP2D) of the Selective Oral MEK1/2 Inhibitor Pimasertib (MSC1936369B/AS703026): Results of a Phase I Trial

Ahmad Awada, J. Delord, Nadine Houédé et al. · European Journal of Cancer · 2012 · 14 citations

Molecular Pharmacology, Medicine, Pharmacology +8

Abstract P2-16-14: Preliminary safety, pharmacokinetics and anti-tumor activity of BYL719, an alpha-specific PI3K inhibitor in combination with fulvestrant: Results from a phase I study

Dejan Juric, AM Gonzalez-Angulo, HA Burris et al. · Cancer Research · 2013 · 12 citations

Breast Oncology, Pathology, Preliminary Safety +18