A. El-Khoueiry

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells

P M Challita, Dianne C. Skelton, A. El-Khoueiry et al. · Journal of Virology · 1995 · 209 citations · Full text

Ec Cells, Epigenetic Change, Genetics +17

Phase I modular study of AZD6738, a novel oral, potent and selective ataxia telangiectasia Rad3-related (ATR) inhibitor in combination (combo) with carboplatin, olaparib or durvalumab in patients (pts) with advanced cancers

Timothy A. Yap, Matthew Krebs, S. Postel-Vinay et al. · European Journal of Cancer · 2016 · 48 citations

Oncology, Advanced Cancers, Medicine +7

LBA O-9 Botensilimab, a novel innate/adaptive immune activator, plus balstilimab (anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer

Andrea J. Bullock, Joseph E. Grossman, Marwan Fakih et al. · Annals of Oncology · 2022 · 48 citations

Cancer Immunosurveillance, Medicine, Immunology +6

Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer

Pierre Bohanes, Dongyun Yang, Fotios Loupakis et al. · The Pharmacogenomics Journal · 2014 · 14 citations

Tumor Biology, Stage Ii, Gastrointestinal Oncology +11

A first-in-human phase I study of sEphB4-HSA in patients with advanced solid tumors with expansion at the maximum tolerated dose (MTD) or recommended phase II dose (RP2D)

A. El-Khoueiry, Barbara J. Gitlitz, Sarah Cole et al. · European Journal of Cancer · 2016 · 14 citations

First-in-human Phase, Medicine, Metronomic Therapy +7