Emily R. Weikum

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

William Henry Hudson, Ian Mitchelle S. de Vera, J.C. Nwachukwu et al. · Nature Communications · 2018 · 131 citations · Full text

Life Sciences, Molecular Biology, Gene Expression +16

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Emily R. Weikum, Ian Mitchelle S. de Vera, J.C. Nwachukwu et al. · Nucleic Acids Research · 2017 · 70 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space

William Henry Hudson, Bradley R. Kossmann, Ian Mitchelle S. de Vera et al. · Proceedings of the National Academy of Sciences · 2015 · 37 citations · Full text

Life Sciences, Evolutionary Biology, Molecular Biology +17

Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner

Emily R. Weikum, C. Denise Okafor, Emma H. D’Agostino et al. · Molecular Pharmacology · 2017 · 24 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Nucleotide Binding to ARL2 in the TBCD ∙ ARL2 ∙ β-Tubulin Complex Drives Conformational Changes in β-Tubulin

Joshua W. Francis, Devrishi Goswami, Scott J. Novick et al. · Journal of Molecular Biology · 2017 · 23 citations

Life Sciences, Cell Biology, Molecular Biology +12