David B. Langley

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

Zahra Sabouri, Peter R. Schofield, Keisuke Horikawa et al. · Proceedings of the National Academy of Sciences · 2014 · 236 citations · Full text

General strategy for the generation of human antibody variable domains with increased aggregation resistance

Kip Dudgeon, Romain Rouet, Iris Kokmeijer et al. · Proceedings of the National Academy of Sciences · 2012 · 189 citations · Full text

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments

Cy M. Jeffries, Melissa A. Graewert, Clément Blanchet et al. · Nature Protocols · 2016 · 161 citations · Full text

X-ray Crystallography, Monodisperse Macromolecular Samples, X-ray Spectroscopy +8

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination

Deborah L. Burnett, David B. Langley, Peter Schofield et al. · Science · 2018 · 134 citations · Full text

Genetic Testing, Genetics, Rapid Self/foreign Discrimination +20

The Structure of the KinA-Sda Complex Suggests an Allosteric Mechanism of Histidine Kinase Inhibition

Andrew E. Whitten, David A. Jacques, Boualem Hammouda et al. · Journal of Molecular Biology · 2007 · 88 citations

Protein Function, Signal Transduction, Molecular Physiology +12