Concepedia

A. Tochowicz

AT

Statistics

Publications

7

Citations

323

H-Index

7

Active since

2007

Affiliations

University of California, San Francisco(Current)

Max Planck Institute of Biochemistry

University of Modena and Reggio Emilia

A. Tochowicz is an author at University of California, San Francisco specializing in medicine, natural sciences, and drug discovery.

Top concepts

MedicinePharmacologyTumor BiologyDrug DiscoveryDrug DevelopmentNatural SciencesMolecular BiologyMedicinal ChemistryBiochemistryCell Biology

Publications per year

2007–2015

7

Publications

7

Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity

A. Tochowicz, K. Maskos, Robert Huber et al. · Journal of Molecular Biology · 2007 · 140 citations

Mmp-9 Complexes, Engineering, Coordination Complex +6

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain

A. Tochowicz, Peter Goettig, Richard D. Evans et al. · Journal of Biological Chemistry · 2010 · 55 citations · Full text

Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain

Brian Jones, A. Tochowicz, Yinyan Tang et al. · ACS Medicinal Chemistry Letters · 2015 · 44 citations

Crystal Structure, Bioorganic Chemistry, Aldo-keto Reductase +18

Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase

Outi M. H. Salo‐Ahen, A. Tochowicz, Cecilia Pozzi et al. · Journal of Medicinal Chemistry · 2015 · 26 citations · Full text

Protein Assembly, Molecular Biology, Chemical Biology +20

Inhibitor of Ovarian Cancer Cells Growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase

Emanuele Carosati, A. Tochowicz, Gaetano Marverti et al. · Journal of Medicinal Chemistry · 2012 · 26 citations · Full text

Human Thymidylate Synthase, Tumor Biology, Ovarian Cancer +21

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