Seamus R. Morrone

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1

Zhihong Cheng, Travis L. Biechele, Zhiyi Wei et al. · Nature Structural & Molecular Biology · 2011 · 200 citations

Protein Function, Biochemistry, Extracellular Domain +6

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy

Seamus R. Morrone, Tao Wang, Leeza M. Constantoulakis et al. · Proceedings of the National Academy of Sciences · 2013 · 171 citations · Full text

Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC

Seamus R. Morrone, Mariusz Matyszewski, Xiong Yu et al. · Nature Communications · 2015 · 153 citations · Full text

Structural Basis of PP2A Inhibition by Small t Antigen

Uhn‐Soo Cho, Seamus R. Morrone, Anna Sablina et al. · PLoS Biology · 2007 · 121 citations · Full text

Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment

Seamus R. Morrone, Zhihong Cheng, Randall T. Moon et al. · Proceedings of the National Academy of Sciences · 2012 · 102 citations · Full text