Motoko Unoki

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

Shinya Hayami, John D. Kelly, Hyun‐Soo Cho et al. · International Journal of Cancer · 2010 · 476 citations · Full text

Exogenous Lsd1 Expression, Epigenetic Change, Histone Demethylases +16

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway

Motoko Unoki, Yusuke Nakamura · Oncogene · 2001 · 377 citations

Signal Transduction, Developmental Biology, Signaling Pathway +8

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

Masanori Yoshimatsu, Gouji Toyokawa, Shinya Hayami et al. · International Journal of Cancer · 2010 · 315 citations · Full text

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

Motoko Unoki, Toshihiko Nishidate, Yusuke Nakamura · Oncogene · 2004 · 305 citations

E2f-1 Target, Protein Function, Signal Transduction +7

Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells

Hyun‐Soo Cho, Takehiro Suzuki, Naoshi Dohmae et al. · Cancer Research · 2010 · 250 citations

Histone Modifications, Epigenetic Change, Molecular Biology +17