Shina Caroline Lynn Kamerlin

Enzyme millisecond conformational dynamics do not catalyze the chemical step

Andrei V. Pisliakov, Jie Cao, Shina Caroline Lynn Kamerlin et al. · Proceedings of the National Academy of Sciences · 2009 · 205 citations · Full text

Enzymology, Renormalization Approach, Biochemistry +14

Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions

Andrew J. Adamczyk, Jie Cao, Shina Caroline Lynn Kamerlin et al. · Proceedings of the National Academy of Sciences · 2011 · 204 citations · Full text

Aldo-keto Reductase, Biochemistry, Protein Folding +15

The empirical valence bond model: theory and applications

Shina Caroline Lynn Kamerlin, Arieh Warshel · Wiley Interdisciplinary Reviews Computational Molecular Science · 2011 · 177 citations

Engineering, Complex Systems, Computational Chemistry +23

Force Field Independent Metal Parameters Using a Nonbonded Dummy Model

Fernanda Duarte, Paul Bauer, Alexandre Barrozo et al. · The Journal of Physical Chemistry B · 2014 · 169 citations · Full text

Evolution of chalcone isomerase from a noncatalytic ancestor

Miriam Kaltenbach, Jason R. Burke, Mirco Dindo et al. · Nature Chemical Biology · 2018 · 149 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +3