A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer

Ravi Anchoori, Balasubramanyam Karanam, Shiwen Peng, +11

Cancer Cell

MedicineImmune Checkpoint InhibitorAnti-cancer AgentTumor SuppressorCancer Treatment +4

Fenugreek: A naturally occurring edible spice as an anticancer agent

Shabana Shabbeer, Michelle Sobolewski, Ravi Anchoori, +6

Cancer Biology & Therapy

α,β-Unsaturated Carbonyl System of Chalcone-Based Derivatives Is Responsible for Broad Inhibition of Proteasomal Activity and Preferential Killing of Human Papilloma Virus (HPV) Positive Cervical Cancer Cells

Martina Bazzaro, Ravi Anchoori, Mohana Krishna Reddy Mudiam, +10

Journal of Medicinal Chemistry

Proteasome InhibitorsChemical BiologyPharmaceutical ChemistryBroad InhibitionMedicinal Chemistry +14

Small-Molecule RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer <i>In Vitro</i> and <i>In Vivo</i> via Exacerbating Unfolded Protein Responses

Kathleen Coughlin, Ravi Anchoori, Yoshie Iizuka, +7

Clinical Cancer Research

Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer

Radharani Marik, Madhan Allu, Ravi Anchoori, +3

Cancer Biology & Therapy

Breast OncologyChemoprevention StrategyEstrogen ReceptorPharmacotherapySoy Isoflavone +14

Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer

Srinivas K. Kumar, Indrajit Roy, Ravi Anchoori, +4

Bioorganic & Medicinal Chemistry

Hedgehog SignalingMedicineAdvanced Prostate CancerPharmacotherapyCyclopamine Prodrugs +7

The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression

Leah Randles, Ravi Anchoori, Richard B.S. Roden, +1

Journal of Biological Chemistry

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells

Rachel I. Vogel, Kathleen Coughlin, Alessandra Scotti, +5

Oncotarget

MitophagyUbiquitin-proteasome-system DegradationBreast OncologyApoptosisCancer Biology +18

mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation

Kaushal Asrani, Sanjana Murali, Brandon Lam, +10

Journal of Clinical Investigation

Microphthalmia FamilyMolecular RegulationActive Mtorc1 SignalingCellular PhysiologyNutrient Sensor Mtorc1 +15

Biological evaluation of Paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery

Roppei Yamada, Maya Kostova, Ravi Anchoori, +3

Cancer Biology & Therapy