Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways

Anna M. Blokhuis, Max Koppers, Ewout J. N. Groen, +15

Acta Neuropathologica

TDP-43 controls lysosomal pathways thereby determining its own clearance and cytotoxicity

Christine Leibiger, Jana Deisel, Andreas Aufschnaiter, +5

Human Molecular Genetics

MitophagyApoptosisMolecular BiologyCell DeathLysosomal Pathways +15

Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold

Chao Qi, Bert M. Verheijen, Yasumasa Kokubo, +15

Proceedings of the National Academy of Sciences

Neurodegenerative DiseasesType Ii FilamentsAlzheimer's DiseaseAmyotrophic Lateral SclerosisMedicine +12

Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model

Inbal Maniv, Mahasen Sarji, Anwar Bdarneh, +17

Nature Communications

Evolutionary conservation of the fidelity of transcription

Claire Chung, Bert M. Verheijen, Zoe Navapanich, +18

Nature Communications

Deciphering the Proteome Dynamics during Development of Neurons Derived from Induced Pluripotent Stem Cells

Suzy Varderidou‐Minasian, Bert M. Verheijen, Philipp Schätzle, +3

Journal of Proteome Research

Cerebral OrganoidSocial SciencesNeuronal DevelopmentProteomic TechnologyNeurogenesis +17

The fidelity of transcription in human cells

Claire Chung, Bert M. Verheijen, Xinmin Zhang, +18

Proceedings of the National Academy of Sciences

Epigenetic ChangeGeneticsTranscriptomics TechnologyGene Regulatory NetworkGene Transcription +20

Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA)

Sebastian Rademacher, Bert M. Verheijen, Niko Hensel, +11

Human Molecular Genetics

Molecular BiologyCytoskeletonMusculoskeletal ResearchCellular PhysiologyNeuromuscular Junction +14

Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer's disease

Romina J. G. Gentier, Bert M. Verheijen, Margherita Zamboni, +6

Frontiers in Neuroanatomy

Neurochemical BiomarkersSynaptic SignalingUbiquitin-proteasome SystemAlzheimer's DiseaseTransgenic Mouse Line +21

Activation of the Unfolded Protein Response and Proteostasis Disturbance in Parkinsonism-Dementia of Guam

Bert M. Verheijen, Celina Lussier, Cora Müller-Hübers, +4

Journal of Neuropathology & Experimental Neurology