Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy

Xi Fang, Julius Bogomolovas, Tongbin Wu, +18

Journal of Clinical Investigation

Heart FailureGeneticsMolecular BiologyMolecular GeneticsMetabolic Remodeling +22

Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation

Canzhao Liu, Simone Spinozzi, Jiayu Chen, +12

Circulation

Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells

Jennifer Veevers, Elie N. Farah, Mirko Corselli, +20

Stem Cell Reports

TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation

Xiaofei Lv, Yajuan Zhang, Xiu Liu, +12

Theranostics

Nexilin Is Necessary for Maintaining the Transverse-Axial Tubular System in Adult Cardiomyocytes

Simone Spinozzi, Canzhao Liu, Ze’e Chen, +5

Circulation Heart Failure

A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure

Adam J. Pollak, Canzhao Liu, Aparna Gudlur, +9

eLife

Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation

Erwen Huang, Canzhao Liu, Sijia Liang, +6

Atherosclerosis

InflammationCytokineGranulocyteMedicineScavenger Receptor Expression +8

Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II γ-Dependent Serine727 Phosphorylation Is Required for TMEM16A Ca<sup>2+</sup>-Activated Cl<sup>−</sup> Channel Regulation in Cerebrovascular Cells

Caixia Lin, Xiaofei Lv, Feng Yuan, +6

Circulation Journal

Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells

Canzhao Liu, Xiangyu Li, Ren‐Hong Du, +7

Circulation Journal

Homozygous G650del nexilin variant causes cardiomyopathy in mice

Canzhao Liu, Simone Spinozzi, Wei Feng, +8

JCI Insight