Valère Lounnas

How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms 1 1Edited by J. Thornton

Susanna K. Lüdemann, Valère Lounnas, Rebecca C. Wade · Journal of Molecular Biology · 2000 · 322 citations

Biophysical Modeling, Biochemistry, Buried Active Site +8

Electrostatic steering and ionic tethering in enzyme–ligand binding: Insights from simulations

Rebecca C. Wade, Razif R. Gabdoulline, Susanna K. Lüdemann et al. · Proceedings of the National Academy of Sciences · 1998 · 206 citations

Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a novel functional role for a buried arginine

Peter J. Winn, Susanna K. Lüdemann, Ralph Gauges et al. · Proceedings of the National Academy of Sciences · 2002 · 171 citations · Full text

Molecular Biology, Chemical Biology, Cytochrome P450s +16

A global model of the protein-solvent interface

Valère Lounnas, B. Montgomery Pettitt, G.N. Phillips · Biophysical Journal · 1994 · 156 citations · Full text

Protein Chemistry, Protein-solvent Interface, Protein Assembly +6

How do substrates enter and products exit the buried active site of cytochrome P450cam? 2. Steered molecular dynamics and adiabatic mapping of substrate pathways 1 1Edited by J. Thornton

Susanna K. Lüdemann, Valère Lounnas, Rebecca C. Wade · Journal of Molecular Biology · 2000 · 143 citations

Biochemistry, Buried Active Site, Bioenergetics +9