Douglas Shea

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong et al. · Science · 2024 · 137 citations · Full text

Engineering, Dna Analysis, Molecular Biology +21

Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth

Gregory Gydush, Erica Nguyen, Jin H. Bae et al. · Nature Biomedical Engineering · 2022 · 78 citations · Full text

Biology, Bioinformatics, Long-read Sequencing +15

Single duplex DNA sequencing with CODEC detects mutations with high sensitivity

Jin H. Bae, Ruolin Liu, Eugenia Roberts et al. · Nature Genetics · 2023 · 72 citations · Full text

mRNAs for alpha- and beta-tubulin and flagellar calmodulin are among those coordinately regulated when Naegleria gruberi amebae differentiate into flagellates.

Douglas Shea, C J Walsh · The Journal of Cell Biology · 1987 · 28 citations · Full text

Biology, Class Ii, Protein Expression +15

New poly(A)+RNAs appear coordinately during the differentiation of Naegleria gruberi amebae into flagellates.

Jordan S. Mar, J H Lee, Douglas Shea et al. · The Journal of Cell Biology · 1986 · 22 citations · Full text

Engineering, Genetics, New Poly +17