Michael W. Bolt

Current nonclinical testing paradigm enables safe entry to First-In-Human clinical trials: The IQ consortium nonclinical to clinical translational database

Thomas M. Monticello, Thomas W. Jones, Donna M. Dambach et al. · Toxicology and Applied Pharmacology · 2017 · 177 citations

Pharmacy, Translational Sciences, Translational Medicine +10

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

Nathanael G. Lintner, Kim F. McClure, Donna N. Petersen et al. · PLoS Biology · 2017 · 127 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Disruption of Mitochondrial Function and Cellular ATP Levels by Amiodarone and N-Desethylamiodarone in Initiation of Amiodarone-Induced Pulmonary Cytotoxicity

Michael W. Bolt, Jeffrey W. Card, William J. Racz et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 67 citations

Life Sciences, Cell Biology, Pharmacology +17

Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis

Kim F. McClure, David W. Piotrowski, Donna N. Petersen et al. · Angewandte Chemie International Edition · 2017 · 46 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Factor XIa–specific IgG and a reversal agent to probe factor XI function in thrombosis and hemostasis

Tovo David, Yun Cheol Kim, Lauren K. Ely et al. · Science Translational Medicine · 2016 · 45 citations

Medicine, Hematology, Pharmacology +15