Margaret Fleming

COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease

Katherine Lowe, Elizabeth A. Regan, Antonio Anzueto et al. · Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · 2019 · 181 citations · Full text

Medicine, Clinical Sciences, Internal Medicine +17

The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial

Aaron Winkler, Weiyong Sun, Saurav De et al. · Arthritis & Rheumatology · 2021 · 90 citations · Full text

Life Sciences, Immunology, Pharmacology +17

IRAK4 kinase activity controls Toll-like receptor–induced inflammation through the transcription factor IRF5 in primary human monocytes

Leah Cushing, Aaron Winkler, Scott A. Jelinsky et al. · Journal of Biological Chemistry · 2017 · 71 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Triad of polar residues implicated in pH specificity of acidic mammalian chitinase

Andrea Olland, James C. Strand, Eleonora Presman et al. · Protein Science · 2009 · 70 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults

Somnath Mukhopadhyay, Joseph P. Sypek, Roger Tavendale et al. · Journal of Allergy and Clinical Immunology · 2010 · 68 citations · Full text

Life Sciences, Immunology, Pediatrics +8