Saurav De

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

Courtney A. Lovejoy, Wen‐Di Li, Steven Reisenweber et al. · PLoS Genetics · 2012 · 638 citations · Full text

Life Sciences, Genetics, Oncology +17

A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome

Bari J. Ballew, Joseph Vijai, Saurav De et al. · PLoS Genetics · 2013 · 140 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells

Harry J. Hurley, Hannah K. Dewald, Zachary S Rothkopf et al. · Journal of Leukocyte Biology · 2020 · 90 citations

Life Sciences, Cell Biology, Immunology +17

The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial

Aaron Winkler, Weiyong Sun, Saurav De et al. · Arthritis & Rheumatology · 2021 · 90 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Inhibition of IRF5 hyperactivation protects from lupus onset and severity

Su Song, Saurav De, Victoria L. Nelson et al. · Journal of Clinical Investigation · 2020 · 89 citations · Full text

Life Sciences, Immunology, Molecular Biology +17