Jenny Kaeding

Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver

Jocelyn Trottier, Mélanie Verreault, Susan Grepper et al. · Hepatology · 2006 · 122 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation

Kathy Senekeo‐Effenberger, Shujuan Chen, Erin Brace‐Sinnokrak et al. · Drug Metabolism and Disposition · 2006 · 118 citations

Life Sciences, Genetics, Pharmacology +11

The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice

Mélanie Verreault, Kathy Senekeo‐Effenberger, Jocelyn Trottier et al. · Hepatology · 2006 · 70 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells

Jenny Kaeding, Emmanuel Bouchaert, Julie Bélanger et al. · Biochemical Journal · 2008 · 56 citations

Medicine, Endocrinology, Pharmacology +17

Calcitrol (1α,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells

Jenny Kaeding, Julie Bélanger, Patrick Caron et al. · Molecular Cancer Therapeutics · 2008 · 34 citations · Full text

Medicine, Endocrinology, Pharmacology +17