Guoxiang Shen

Inhibition of 7,12-Dimethylbenz(<i>a</i>)anthracene-Induced Skin Tumorigenesis in C57BL/6 Mice by Sulforaphane Is Mediated by Nuclear Factor E2–Related Factor 2

Changjiang Xu, Mou‐Tuan Huang, Guoxiang Shen et al. · Cancer Research · 2006 · 382 citations · Full text

Medicine, Oncology, Pharmacology +17

Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells

Changjiang Xu, Guoxiang Shen, Chi Chen et al. · Oncogene · 2005 · 300 citations

Medicine, Molecular Biology, Oncology +10

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 277 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2

Changjiang Xu, Xiaoling Yuan, Zui Pan et al. · Molecular Cancer Therapeutics · 2006 · 263 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals

Chi Chen, Daniel Pung, Vasco Leong et al. · Free Radical Biology and Medicine · 2004 · 259 citations

Life Sciences, Biochemistry, Toxicology +17