Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation

Detmar Kolijn, Steffen Pabel, Yanna Tian, +19

Cardiovascular Research

Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies

Simona Manni, Francesca Del Bufalo, Pietro Merli, +22

Nature Communications

Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

Detmar Kolijn, Árṕad Kov́acs, Melissa Herwig, +14

Frontiers in Physiology

Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D

Melissa Herwig, Detmar Kolijn, Mária Lódi, +12

Frontiers in Physiology

CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect

Jan‐Christian Reil, Gert‐Hinrich Reil, Árṕad Kov́acs, +17

The Journal of Physiology

Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy

Roua Hassoun, Heidi Budde, Saltanat Zhazykbayeva, +20

International Journal of Cardiology

The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts

Heidi Budde, Roua Hassoun, Melina Tangos, +18

Antioxidants

SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress

Melina Tangos, Heidi Budde, Detmar Kolijn, +24

International Journal of Cardiology

Advantages of prophylactic versus conventionally scheduled heart failure therapy in an experimental model of doxorubicin-induced cardiomyopathy

Mária Lódi, Dániel Priksz, Gábor Áron Fülöp, +16

Journal of Translational Medicine

Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart

Viktor Bánhegyi, Attila Enyedi, Gábor Áron Fülöp, +18

Cells